Advances in Medicinal Chemistry: 5 by A. B. Reitz,S. L. Dax

By A. B. Reitz,S. L. Dax

quantity five of Advances in Medicinal Chemistry comprises 4 fascinating and particular debts of the shut interface among man made chemistry, structure-activity relationships, biochemistry, and pharmacology. In bankruptcy 1, there's a entire survey of the immunophilin zone in particular focussing on neuroregenerative purposes within the relevant fearful process. In bankruptcy 2, there's an summary of the advance of a powerful analgesic compound that works through modulation of neuronal nicotinic acetylcholine receptors. In bankruptcy three, there's a description of dopamine D-2 autoreceptor partial agonists as power remedy for the remedy of schizophrenia. In bankruptcy four, there's a precis of the winning application during which powerful non-peptide inhibitors of HIV protease from the AIDS virus have been built.

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